How Does XEOMIN® Work?
Frown lines form when facial expressions are made as the muscle under the skin contracts. Over time, as your skin ages, these repeated expressions cause lasting frown lines. Neurotoxins, such as XEOMIN®, are prescription medications that block the release of chemicals that cause these muscle contractions. So frown lines are softened.
XEOMIN® contains botulinum toxin type A, a protein purified from the bacterium Clostridium botulinum. Botulinum toxin type A acts on nerve endings in muscles to prevent muscle fibers from contracting. By reducing these contractions, XEOMIN® can temporarily reduce the lines on your forehead between your brows.
XEOMIN® (incobotulinumtoxinA) is a prescription medication used to temporarily improve the appearance of moderate to severe frown lines between the eyebrows (glabellar lines) in adults.
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Indication & Usage
XEOMIN® is a prescription medicine that is injected into muscles and used to improve the look of moderate to severe frown lines between the eyebrows (glabellar lines) in adults for a short period of time (temporary).
IMPORTANT SAFETY INFORMATION (CONTINUED)
Swallowing problems may last for several months. People who cannot swallow well may need a feeding tube to receive food and water. If swallowing problems are severe, food or liquids may go into your lungs. People who already have swallowing or breathing problems before receiving XEOMIN® have the highest risk of getting these problems.
Spread of toxin effects. In some cases, the effect of botulinum toxin may affect areas of the body away from the injection site and cause symptoms of a serious condition called botulism.
The symptoms of botulism include:
- loss of strength and muscle weakness all over the body
- double vision
- blurred vision and drooping eyelids
- hoarseness or change of loss of voice
- trouble saying words clearly
- loss of bladder control
- trouble breathing
- trouble swallowing
These problems could make it unsafe for you to drive a car or do other dangerous activities.
Active Ingredient: incobotulinumtoxinA
Purpose: acts on nerve endings in muscles to prevent muscle fibers from contracting
Do not use XEOMIN if you are allergic to XEOMIN® or any of the ingredients in XEOMIN® (see the end of the Medication Guide for a list of ingredients in XEOMIN®), had an allergic reaction to any other botulinum toxin products such as rimabotulinumtoxinB (MYOBLOC®), onabotulinumtoxinA (BOTOX®, BOTOX® COSMETIC), or abobotulinumtoxinA (DYSPORT®) or have a skin infection at the planned injection site.
- Ask a doctor before use if you have a disease that affects your muscles and nerves (such as amyotrophic
lateral sclerosis [ALS or Lou
Gehrig’s disease], myasthenia gravis or Lambert-Eaton syndrome)
- have allergies to any botulinum toxin product
- have had any side effect from any other botulinum toxin in the past
- have a breathing problem, such as asthma or emphysema
- have a history of swallowing problems or inhaling food or uid into your lungs (aspiration)
- have bleeding problems
- have drooping eyelids
- have plans to have surgery
- have had surgery on your face
- are pregnant or plan to become pregnant. It is not known if XEOMIN® can harm your unborn baby.
- are breastfeeding or plan to breastfeed. It is not known if XEOMIN® passes into breast milk.
XEOMIN® is not recommended for use in children younger than 18 years of age.
Tell your doctor about all of your medical conditions and all of the medicines you take, including prescription and nonprescription medicines, vitamins and herbal supplements. Do not start any new medicines until you have told your doctor that you have received XEOMIN® in the past.
Especially tell your doctor if you
- have received any other botulinum toxin product in the last four months
- have received injections of botulinum toxin such as rimabotulinumtoxinB (MYOBLOC®), onabotulinumtoxinA (BOTOX®,BOTOX® COSMETIC) and abobotulinumtoxinA (DYSPORT®) in the past. Be sure your doctor knows exactly which product you received. The dose of XEOMIN® may be different from other botulinum toxin products that you have received.
- have recently received an antibiotic by injection
- take muscle relaxants
- take an allergy or cold medicine
- take a sleep medicine
- take a blood thinner medicine
- Ask your doctor if you are not sure if your medicine is one that is listed above.
Possible Side Effects
XEOMIN can cause serious side effects that can be life threatening. See “Warnings.”
- dry mouth
- discomfort or pain at the injection site
- neck pain
- muscle weakness
- eye problems, including: double vision, blurred vision, drooping eyelids, swelling of your eyelids, and dry eyes. Reduced blinking can also occur. Tell your doctor or get medical help right away if you have eye pain or irritation following treatment.
XEOMIN may cause other serious side effects including allergic reactions. Symptoms of an allergic reaction to XEOMIN® may include: itching, rash, redness, swelling, wheezing, asthma symptoms, or dizziness or feeling faint. Tell your doctor or get medical help right away if you get wheezing or asthma symptoms, or if you get dizzy or faint.
Tell your doctor if you have any side effect that bothers you or that does not go away.
These are not all the possible side effects of XEOMIN®. For more information, talk to your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
- XEOMIN® is a shot (injection) that your doctor will give you.
- XEOMIN® is injected into your affected muscles.
- Your doctor may change your dose of XEOMIN® until you and your doctor find the best dose for you.
- Inactive Ingredients: human albumin and sucrose
Read the Medication Guide before you start receiving XEOMIN® and each time XEOMIN® is given to you as there may be new information. The risk information provided here is not comprehensive. To learn more:
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